model：
brand：lci
specifications ：
introduction：lci产制满足各种应用培养系统
lci产制满足各种应用培养系统
multistep paradigm for leukocyte recruitment
(a)model of a post-capillary venule illustrating the four steps of leukocyte recruitment.these are(1)initial attachment(2)low-velocity rolling(3)arrest and activation of leukocyte integrin via locally expressed chemokines and(4)transmigration.(b)fluid shear stress.in small venules,flow has been calculated as laminar shear stress with a parabolic velocity profile(minimum velocity at the vessel wall,maximum at the center line of the vessel).fluid shear stress also can act directly on endothelial cells and t cells.(ec,endothelial cell;bm,basement membrane.)(reprinted with permission from alper,j.searching for medicine's sweet spot.science 291,2338−2243(2001).).z6尊龙app copyright american association for the advancement of science.original illustration by c.cain,redrawn by b.crimi.)
